Tumors of the Central Nervous System, Volume 4: Brain Tumors (Part 2)

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Description

This volume mainly contains information on the diagnosis, therapy, and prognosis of brain tumors. Insights on the understanding of molecular pathways involved in tumor biology are explained, which should lead to the development of effective drugs. Information on pathways (e.g., hedgehog) facilitates targeted therapies in cancer. Tumor models are also presented, which utilize expression data, pathway sensitivity, and genetic abnormalities, representing targets in cancer. For example, rat model of malignant brain tumors using implantation of doxorubicin with drug eluting beads for delivery is explained. The future of pathway-driven therapies for tumors is summarized. The importance of personalizing cancer care is emphasized. The need for supportive measures for survivors of brain cancer is pointed out, so is the quality of life monitoring. The need of rehabilitation therapy for patients with primary and metastatic brain tumors is also emphasized. Role of MicroRNA in distinguishing primary tumors from metastatic primary tumors is discussed. Advantages and limitations of chemotherapy (e.g., temozolomide and doxorubicin) are discussed. The complexity of tumor to tumor transfer is explained; examples discussed are: brain metastases from breast cancer and brain metastases fro non-small cell lung carcinoma. Identification and characterization of biomarkers, including those for metastatic brain tumors, are presented. Genomic analysis for identifying clinically relevant subtypes of glioblastoma is included. A large number of imaging modalities are detailed to study progression and invasion of gliomas

Additional information

PackageQuantity

1

PartNumber

biography

PackageDimensions
NumberOfPages

386

NumberOfItems

1

ProductGroup

Book

ProductTypeName

ABIS_BOOK

Title

Tumors of the Central Nervous System, Volume 4: Brain Tumors (Part 2)

Studio

Springer

Publisher

Springer

PublicationDate

2011-09-08

MPN

biography

Manufacturer

Springer

EANList
EAN

9789400717053

Creator

M.A. Hayat

Brand

Springer

Edition

2012

ISBN

9400717059

ListPrice
Languages
Label

Springer

ItemDimensions
Binding

Hardcover